[478392-41-5]    

MFCD04037006

Synonyms : (E)-Octyl 3-(3,4-dihydroxyphenyl)acrylate; Octyl caffeate

Applications : n-Octyl caffeate exhibits antioxidative, anti-metastatic, anticancer chemotherapeutic, and chemopreventive activities. n-Octyl caffeate decreases lipid peroxidation, activity of xanthine oxidase, activation of JNK and ERK, and production of NO and iNOS in rat brain homogenate; it also prevents the LPS-induced drop in mean arterial pressure in aortic smooth muscle cells. In animal models of tumor metastasis, n-octyl caffeate decreases tumor nodules.

References : Nagaoka. T. et el.; Biol. Pharm. Bull., 26(5), 638-41, 2003; PMID 12736504; Hsiao. G. et al.: Biochem. Pharmacol., 15, 65(8), 1383-92, 2003; PMID 12694879.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.