Bisindolylmaleimide II-d<sub>3</sub>





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SL-1233

Bisindolylmaleimide II-d3, 98% (CP)

 
Isotopic Purity : 99 atom % D
Related CAS No. : [137592-45-1] of the unlabelled compound
Synonym (s) : 3-(1H-Indol-3-yl)-4-(1-(2-(1-methyl-d3 pyrrolidin-2-yl)ethyl)-1H-indol-3-yl)-1H-pyrrole-2,5-dione
Price and Availability
Pack SizePrice in USDQuantityAvailabilityShipping Status
10MG3980.00Back Order Estimated to Ship on 03.20.2018
Chemical Properties
Mol. Formula : C27H23D3N4O2Appearance : Solid
Mol. Weight : 441.54Melting Point : Not available
     For Laboratory research use only, not for drug, household or other uses.
Applications : It is a deuterium labelled version of Bisindolylmaleimide II. Which is a potent ATP-competitive protein kinase C (PKC) inhibitor. Also it inhibits PDK1 (IC50 = 14 μM), an important kinase in the insulin signaling pathway, and PKA (IC50 = 2.94 μM).
Reference : Davis. P.D. et al.: J. Med. Chem., 35, 177-184,1992.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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