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SL-344 

PD153035-d6 hydrochloride, 98% (CP)

Isotopic Purity : 
99 atom % D
MDL No. : 
MFCD28386062
Related CAS No. : 
[183322-45-4] of the unlabelled compound
Synonyms : 4-​[(3-​Bromophenyl)​amino]​-​6,7-​dimethoxy-d6-quinazoline hydrochloride

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MG480.00 In Stock Available to Ship on 03.29.2024
25MG1880.00 In Stock Available to Ship on 03.29.2024
Chemical Properties
C16H8D6BrN3O2 · HCl 402.70
Beige solid 257-260oC
DMSO
For Laboratory research use only, not for drug, household or other uses.
Applications : Labelled analogue of PD153035, has been found to inhibit EGF-dependent EGFR phosphorylation in a variety of human cancer cell lines over-expressing EGFRs, which include A431, Difi, DU145, MDA-MB-468, ME180 and C4i, with IC50 of 0.22 μM, 0.3 μM, 0.4 μM, 0.68 μM, 0.95 μM and 2.5 μM respectively leading to suppression of proliferation and clonogenicity in those cell lines.
References : Mendelsohn B M.et. al.: Clin Cancer Res., 3(11), 2099,1997.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term storage.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-344

Product Name : PD153035-d6 hydrochloride

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