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SL-672 

O6-[3-(Trifluoroacetamidomethyl)benzyl]guanine, 97%

CAS No. : 
[1055972-09-2]    
MDL No. : 
MFCD30146116
Synonyms : N-(3-((2-Amino-9H-purin-6-yloxy)methyl)benzyl)-2,2,2-trifluoroacetamide

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
25MG980.00 In Stock Available to Ship on 04.18.2024
100MG2980.00 In Stock Available to Ship on 04.18.2024
Chemical Properties
C15H13F3N6O2 366.30
White solid 220-222oC (lit.)
DMSO
For Laboratory research use only, not for drug, household or other uses.
Applications : O6-[3-(Trifluoroacetamidomethyl)benzyl]guanine is the precursor for O6-[3-(Aminomethyl)benzyl] guanine, it was observed that the substitution of aminomethyl at the meta-position enhances the inactivation of O6-alkylguanine-DNA alkyltransferase by O6- benzylguanine, could be useful intermediate inorder to find out the suitable chemotherapeutic DNA-alkylating agents.
References : Pauly. G. T. et. al.: J. Med. Chem., 51, 7144, 2008.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-672

Product Name : O6-[3-(Trifluoroacetamidomethyl)benzyl]guanine

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