NO-Aspirin 1





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SL-985

NO-Aspirin 1, 97%

 
CAS No. : [175033-36-0]          MDL No. : MFCD01939436
Synonym (s) : 2-(Acetyloxy)benzoic acid 3-(nitroxymethyl)phenyl ester; NCX 4016
Price and Availability
Pack SizePrice in USDQuantityAvailabilityShipping Status
10MG100.00Back Order Estimated to Ship on 12.05.2017
25MG120.00Back Order Estimated to Ship on 12.05.2017
50MG230.00Back Order Estimated to Ship on 12.05.2017
100MG450.00Back Order Estimated to Ship on 12.05.2017
250MG980.00Back Order Estimated to Ship on 12.05.2017
Chemical Properties
Mol. Formula : C16H13NO7Appearance : Off-white solid
Mol. Weight : 331.28Melting Point : 62-64oC (lit.)
     For Laboratory research use only, not for drug, household or other uses.
Applications : NO-Aspirin 1 is a hybrid molecule of aspirin and a nitric oxide (NO) donor. It contains an ester linkage, that when cleaved by esterases in the gut, liver, and plasma releases salicylate and an NO-releasing moiety. It also prevents restinosiis, inhibits proliferation of vascular smooth muscle cells, reduces infarct ssize following cardiac ischemia, and exhibits strong chemopreventative effects against colon cancer development.
Reference : Wallace J.L. et al.: Nature Reviews Drug Discovery, 1, 375, 2002; Chiroli V. et al.: Eur. J. Med. Chem., 38, 441, 2003.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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