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SL-342 

AG-1478-d6 hydrochloride, >98% (CP)

Isotopic Purity : 
99 atom % D
MDL No. : 
MFCD28386061
Related CAS No. : 
[170449-18-0] of the unlabelled compound
Synonyms : 6,7-Dimethoxy-d6-4-(3'-chloroanilino)quinazoline hydrochloride; Tyrphostin AG-1478-d6 hydrochloride; NSC 693255-d6 hydrochloride

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MG480.00
-
+
In Stock Available to Ship on 04.26.2024
25MG1880.00
-
+
In Stock Available to Ship on 04.26.2024
Chemical Properties
C16H8D6ClN3O2 . HCl 358.25
Off-white solid 258-260oC
DMSO
For Laboratory research use only, not for drug, household or other uses.
Applications : This is the deuterium labelled analog of AG-1478 hydrochloride. A selective EGFR tyrosine kinase inhibitor with IC50 of 3 nM. AG-1478 hydrochloride has antiviral effects against HCV and encephalomyocarditis virus (EMCV).
References : Jo M. et. al.: J. Bio. Chem., 275(12), 8806, 2000; Bojko A. et al.: Folia Histochem Cytobiol., 50(2), 186-195, 2012; Li W. et al.: Sci Rep., 6, 24580, 2016; Akhtar S. et al.: PLoS One 10(7), e0132215, 2015; Dorobantu C. M. et al.: Antimicrob Agents Chemother., 60(10), 6402-6, 2016.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term storage.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-342

Product Name : AG-1478-d6 hydrochloride

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