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1-(2-(3-Fluoro-5-(trifluoromethyl)phenyl)acetyl)indoline-5-boronic acid pinacol ester

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SI-3754

1-(2-(3-Fluoro-5-(trifluoromethyl)phenyl)acetyl)indoline-5-boronic acid pinacol ester, 97%

CAS No. : [1644664-23-2]

IUPAC Name : 2-(3-Fluoro-5-(trifluoromethyl)phenyl)-1-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indolin-1-yl)ethanone

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100MGRequest A Quote
Back Order  Estimated to ship on 20 September 2026
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Back Order  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C23H24BF4NO3
Mol. Weight :
449.25
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an advanced key intermediate in the preparation of SI-3721 and related analogs, which is a potent and selective protein kinase R‑like endoplasmic reticulum kinase (PERK) inhibitor.

References : Smith L. A. et al.: J. Med. Chem., 58(3), 1426-1441, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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