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1,2-Dihydro loteprednol

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1,2-Dihydro loteprednol, >98%

CAS No. : [82034-20-6]

IUPAC Name : Chloromethyl (8S,9S,10R,11S,13S,14S,17R)-17-((ethoxycarbonyl)oxy)-11-hydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-17-carboxylate

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Chemical Properites
Mol. Formula :
C24H33ClO7
Mol. Weight :
468.97
Appearance :
Light brown solid
Melting Point :
Not available
Solubility :
DCM
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Prednisolone, which is a potent, orally active corticosteroid and a glucocorticoid. It offers four times the anti-inflammatory effect of hydrocortisone with reduced salt and water retention, and is useful in ocular and anti-inflammatory research.

References : Prednisolone J. Am. Pharm. Assoc., 16(3), 143-146, 1976; Musson D. G. et al.: J. Chromatogr. 565(1-2), 89-102, 1991; Hahn B. H. et al.: Arthritis & Rheumatism: Official Journal of the American College of Rheumatology, 16(2), 163-170, 1973; Nowell P.C. Cancer Res., 21, 1518-21, 1961.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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