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1-((2-Fluorophenyl)carbamoyl)cyclopropane-1-carboxylic acid

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SL-7399

1-((2-Fluorophenyl)carbamoyl)cyclopropane-1-carboxylic acid, >98%

CAS No. : [918642-61-2]

MDL No. : MFCD16676129

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
100MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
250MGRequest A Quote
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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C11H10FNO3
Mol. Weight :
223.20
Appearance :
Beige solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an advanced key intermediate in the preparation of Cabozantinib related analogs. Cabozantinib is an inhibitor of the tyrosine kinases c-Met and VEGFR2, and also inhibits AXL and RET. It is used to treat medullary thyroid cancer, renal cell carcinoma, and hepatocellular carcinoma.

References : You W. K. et al.: Cancer Res., 71(14), 4758-4768, 2011; Torres K. E. et al.: Clin Cancer Res., 17(12), 3943-3955, 2011; Yakes F. M. et al.: Mol Cancer Ther., 10(12), 2298-2308, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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