(1-((2-(Trimethylsilyl)ethoxy)methyl)-3-(1-((2-(trimethylsilyl)ethoxy)methyl)-1H-benzo[d]imidazol-2-yl)-1H-indazol-6-yl)boronic acid pinacol ester

SI-1105

(1-((2-(Trimethylsilyl)ethoxy)methyl)-3-(1-((2-(trimethylsilyl)ethoxy)methyl)-1H-benzo[d]imidazol-2-yl)-1H-indazol-6-yl)boronic acid pinacol ester, 97%

CAS No. : [2082789-55-5]

IUPAC Name : 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-3-(1-((2-(trimethylsilyl)ethoxy)methyl)-1H-benzo[d]imidazol-2-yl)-1H-indazole

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Applications : This is an advanced key intermediate in the preparation of PF-06263276 and related analogs, which is a potent, selective pan JAK inhibitor.

References : Jones P. et al.: J. Med. Chem., 60(2), 767-786,2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.