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1-(3-Cyano-5-oxo-5,7-dihydrofuro[3,4-b]pyridin-2-yl)-4-methyl-N-((4-methylbenzyl)sulfonyl)piperidine-4-carboxamide

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SI-3620

1-(3-Cyano-5-oxo-5,7-dihydrofuro[3,4-b]pyridin-2-yl)-4-methyl-N-((4-methylbenzyl)sulfonyl)piperidine-4-carboxamide, >98% (HPLC)

CAS No. : [2299200-91-0]

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Chemical Properites
Mol. Formula :
C23H24N4O5S
Mol. Weight :
468.53
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an analog of AZD-1283, showed significantlyenhanced metabolic stability in subsequent structure− pharmacokinetic relationship studies. A P2Y12 antagonist, an oral antiplatelet agent with improved druglike properties. A promising drug candidate.

References : Kong D. et al.: J. Med. Chem., 62(6), 3088-3106, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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