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1-Acetyl-4-(4-hydroxyphenyl)piperazine

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SL-4815

1-Acetyl-4-(4-hydroxyphenyl)piperazine, >98%

CAS No. : [67914-60-7]

MDL No. : MFCD00044905

Synonyms : Ketoconazole impurity 11

IUPAC Name : 1-(4-(4-Hydroxyphenyl)piperazin-1-yl)ethan-1-one

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
1G8.00
In Stock  Estimated to ship on 20 September 2026
5G10.00
In Stock  Estimated to ship on 20 September 2026
25G15.00
In Stock  Estimated to ship on 20 September 2026
100G40.00
In Stock  Estimated to ship on 20 September 2026
500G145.00
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C12H16N2O2
Mol. Weight :
220.27
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an advanced key intermediate in the preparation of Ketoconazole and related analogs, which is an inhibitor of cyclosporine oxidase and testosterone 6 beta-hydroxylase, used to treat certain serious fungal infections in the body.

References : Oliver W. R Jr. et al.: Proc. Natl. Acad. Sci., U S A, 98(9), 5306-5311, 2001; Eil C. et al.: Horm Metab Res, 24(8), 367-370, 1992; Forgue-Lafitte M. E. et al. Cancer Res, 52(24), 6827-6831, 1992; Gupta A. K. et al.: Br. J. Dermatol, 142(4), 758-765, 2000; Goeders N. E. et al.: Drug Alcohol Depend, 53(1), 67-77, 1998; Salphati L. et al.: Pharmacology, 56(6), 308-313, 1998.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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