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1-Demethyl thiocolchicine

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SL-6543

1-Demethyl thiocolchicine, >98%

IUPAC Name : (S)-N-(1-Hydroxy-2,3-dimethoxy-10-(methylthio)-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide

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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C21H23NO5S
Mol. Weight :
401.48
Appearance :
Pale yellow solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : 1-Demethyl thiocolchicine is a metabolite and an impurity of Thiocolchicine, which is an antimitotic alkaloid and apoptosis inducer that inhibits tubulin polymerization and microtubule assembly.

References : Sharma S. et al.: Biochem., 49, 2932, 2010; Bartusik D. et al.: Bioorg. Chem., 38, 1, 2010; Passarella D. et al.: Eur. J. Med. Chem., 45, 219, 2010.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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