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1-Hydroxy fingolimod

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SL-3228

1-Hydroxy fingolimod, >98%

CAS No. : [162361-49-1]

Related CAS No. : [268557-51-3] of the HCl salt compound

Synonyms : Fingolimod impurity 6

IUPAC Name : 3-Amino-3-(hydroxymethyl)-1-(4-octylphenyl)butane-1,4-diol

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Chemical Properites
Mol. Formula :
C19H33NO3
Mol. Weight :
323.47
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : 1-Hydroxy fingolimod is an impurity of Fingolimod, which is a sphingosine 1-phosphate (S1P) antagonist and an immunomodulating agent for the treatment of multiple sclerosis.

References : Rolin J. et al.: Cancer Immunol Immunother. 59(4), 575-586, 2010; Szepanowski F. et al.: J. Neuroinflammation 13(1), 143, 2016; Airas L. et al.: J. Nucl. Med., 56(2), 305-310, 2015; Shirakabe K. et al.: J Gastroenterol Hepatol., Jan 15, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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