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1-Methylbiguanide sulfate

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SL-4424

1-Methylbiguanide sulfate, >98%

CAS No. : [36801-25-9]

Synonyms : N-Methylimidodicarbonimidic diamide sulfate; N-Desmethylmetformin sulfate; Metformin EP impurity E

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Chemical Properites
Mol. Formula :
C3H9N5 . H2SO4
Mol. Weight :
213.21
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity or metabolite of Metformin, which is decreases hyperglycemia in hepatocytes primarily by suppressing glucose production by the liver (hepatic gluconeogenesis).

References : Zhou G. et al.: J. Clin Invest, 108(8), 1167-1174, 2001; Shaw R. J. et al.: Science, 310(5754), 1642-1646, 2005; Fryer L. G. et al.: J. Biol Chem, 277(28), 25226-25232, 2002; Schmidt L. J. et al.: Prostate, 67(10), 1111-1120, 2007.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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