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1-Methylxanthine-d3

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SL-4155

1-Methylxanthine-d3, >98% (CP)

Isotopic Purity : 99 atom % D

CAS No. : [1216430-61-3]

IUPAC Name : 1-Methyl-1H-purine-2,6(3H,9H)-dione-d3

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Chemical Properites
Mol. Formula :
C6H3D3N4O2
Mol. Weight :
169.16
Appearance :
Pale beige solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : 1-Methylxanthine-d3 is a deuterium labelled version metabolite of Theophylline, which is a nonselective phosphodiesterase (PDE) inhibitor, adenosine receptor blocker, and histone deacetylase (HDAC) activator; used in therapy for respiratory diseases such as chronic obstructive pulmonary disease (COPD) and asthma.

References : Deree J. et al.: Clinics (Sao Paulo) 63(3), 321-328, 2008; Marques L. J. et al.: Am J. Respir Crit Care Med., 159(2), 508-511, 1999; Daly J. W. et al.: Prog Clin Biol Res., 230, 41-63, 1987.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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