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10-(3-bromopropyl)-2-(trifluoromethyl)-10H-phenothiazine

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10-(3-bromopropyl)-2-(trifluoromethyl)-10H-phenothiazine, >98%

CAS No. : [1675-43-0]

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Chemical Properites
Mol. Formula :
C16H13BrF3NS
Mol. Weight :
388.25
Appearance :
White solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an advanced key intermediate in the preparation of Fluphenazine and related analogs. Fluphenazine is a phenothiazine-class D1DR and D2DR inhibitor; used to deliver Fluphenazine to biological systems in studies probing the effects and metabolic fates of this commonly used dopamine antagonist.

References : Trzeciak H. I. et al.: Arzneimittelforschung. 26(9), 1697-700, 1976; Whelpton R. Curry S. H. et al.: J. Pharm. Pharmacol., 28(12), 869-873,1976; Javaid J. I. et al.: J. Chromatogr Sci.,19(9), 439-443, 1981.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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