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12-Hydroxy nevirapine

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SL-11133

12-Hydroxy nevirapine, >98%

CAS No. : [133627-24-4]

Synonyms : 12-Hydroxy-NVP; 12-OH-NVP

IUPAC Name : 11-Cyclopropyl-4-(hydroxymethyl)-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

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Chemical Properites
Mol. Formula :
C15H14N4O2
Mol. Weight :
282.3
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a metabolite of Nevirapine, which belongs to the class of antiretroviral agents called non-nucleoside reverse transcriptase inhibitors (NNRTIs), used to treat HIV-1 infection and AIDS.

References : Podzamczer. D. et al.: Expert Opin. Pharmacother., 2(12), 2065, 2001; Ana M. et al.: Expert Rev. Anti Infect. Ther., 2(3), 367, 2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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