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16-alpha-Hydroxycortisol

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SL-5332

16-alpha-Hydroxycortisol, >98%

CAS No. : [1171-81-9]

Synonyms : 11β,16α,17,21-Tetrahydroxy-pregn-4-ene-3,20-dione; 16α,17-Dihydroxy-corticosterone

IUPAC Name : (8S,9S,10R,11S,13S,14S,16R,17S)-11,16,17-Trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one

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Chemical Properites
Mol. Formula :
C21H30O6
Mol. Weight :
378.47
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Budesonide, which is a glucocorticoid steroid for the treatment of asthma, non-infectious rhinitis.

References : Stellato C. et al.: J. Immunol., 163(10), 5624-5632, 1999; Bandi N. et al.: Eur J. Pharmacol., 425(2), 109-116, 2001; Ek A. et al.: Allergy 54(7), 691-699, 1999; Jansson A. H. et al.: Vascul Pharmacol., 43(2), 101-111, 2005; Yao R. et al.: Oncogene 23(46), 7746-7752, 2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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