1HMT-PI3Kd-372

SI-7344

1HMT-PI3Kd-372, >98% (HPLC)

CAS No. : [2429889-61-0]

IUPAC Name : (S)-2-(1-(4-Amino-3-(3-fluoro-4-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)propyl)-3-cyclopropylquinazolin-4(3H)-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : This selectively targets PI3Kδ with low‑nanomolar potency (IC₅₀ = 14 nM) and shows pronounced selectivity over other class I PI3Ks (56–83‑fold) and diverse protein kinases. This profile makes it a valuable tool compound for investigating PI3Kδ‑driven inflammatory pathways relevant to COPD.

References : Li F. et al.: J. Med. Chem., 63(22), 13973-13993, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.