(1R,2S,5S)-3-((S)-2-(3-(1-((tert-Butylsulfonyl)methyl)cyclohexyl)ureido)-3,3-dimethylbutanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic acid

SI-3221

(1R,2S,5S)-3-((S)-2-(3-(1-((tert-Butylsulfonyl)methyl)cyclohexyl)ureido)-3,3-dimethylbutanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic acid, 97%

CAS No. : [1208245-90-2]

MDL No. : MFCD22124666

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Applications : This is an advanced key intermediate in the preparation of Narlaprevir and related analogs, which is a potent, selective, orally bioavailable NS3 protease inhibitor.

References : Flick C. A. et al.: J. Med. Chem., 61(16), 7004-7031, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.