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(1r,4r)-6′-Bromo-4-methoxy-1′ -methylene-1′,3′-dihydrospiro[cyclohexane-1,2′-indene]

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SI-954

(1r,4r)-6′-Bromo-4-methoxy-1′ -methylene-1′,3′-dihydrospiro[cyclohexane-1,2′-indene], 97%

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
100MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
500MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C16H19BrO
Mol. Weight :
307.23
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an advanced intermediate in the preparation of SI-953 and related analogs, which is a BACE1 inhibitor (β‑secretase‑1).

References : Johansson P. et al.: J. Med. Chem., 61(8), 3491-3502, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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