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(1R)-AZD-1480

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SI-6453

(1R)-AZD-1480, >98% (HPLC)

CAS No. : [935666-99-2]

IUPAC Name : (R)-5-Chloro-N2-(1-(5-fluoropyrimidin-2-yl)ethyl)-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine

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Chemical Properites
Mol. Formula :
C14H14ClFN8
Mol. Weight :
348.77
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : (1R)-AZD‑1480 represents the (1R) chiral isomer of the ATP‑competitive JAK1/2 inhibitor AZD‑1480, supporting studies of stereochemical effects on kinase inhibition and JAK/STAT signaling modulation.

References : Derenzini E. et al.: Blood Cancer J. 1(12), e46, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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