{(1S,1′R,3S,4S)-4-Methoxy-3-methyl-6′-(pyrimidin-5-yl)-3′H,5″H-dispiro[cyclohexane-1,2′-indene-1′,4″-oxazol]-5″,5″-d2-2″-amine}

SI-953

{(1S,1′R,3S,4S)-4-Methoxy-3-methyl-6′-(pyrimidin-5-yl)-3′H,5″H-dispiro[cyclohexane-1,2′-indene-1′,4″-oxazol]-5″,5″-d2-2″-amine}, >98% (HPLC)

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 01 November 2026
25MG	Request A Quote		Back Order	Estimated to ship on 01 November 2026
100MG	Request A Quote		Back Order	Estimated to ship on 01 November 2026
250MG	Request A Quote		Back Order	Estimated to ship on 01 November 2026
500MG	Request A Quote		Back Order	Estimated to ship on 01 November 2026
Note: SI-953 is not in stock but can be available through custom synthesis. The estimated lead-time is 8-10 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or Request A Quote. We will respond promptly. Thank You!

Applications : SI-953 is a BACE1 inhibitor (β‑secretase‑1). BACE1 is responsible for the first step in APP proteolysis, leading to toxic Aβ production, and has been indicated to play a key role in the pathogenesis of Alzheimer’s disease.

References : Johansson P. et al.: J. Med. Chem., 61(8), 3491-3502, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.