(1S,3'R,4'S,5'S,6'R)-6,6'-Bis(hydroxymethyl)-3',4',5',6'-tetrahydro-3H-spiro[isobenzofuran-1,2'-pyran]-3',4',5'-triol

SI-3573

(1S,3'R,4'S,5'S,6'R)-6,6'-Bis(hydroxymethyl)-3',4',5',6'-tetrahydro-3H-spiro[isobenzofuran-1,2'-pyran]-3',4',5'-triol, 97%

CAS No. : [903566-65-4]

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Applications : This is an advanced key intermediate in the preparation of Tofogliflozin and related analogs, which is a potent and highly specific sodium/glucose cotransporter 2(SGLT2) inhibitor.

References : Flick C. A. et al.: Bioorg. Med. Chem. 24(9), 1937-1980, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.