(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride

SL-6289

(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride, >98%

CAS No. : [866783-13-3]

MDL No. : MFCD13194843

Related CAS No. : [866783-12-2] of the free base compound

IUPAC Name : (S)-1-(3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)-N-methylmethanamine hydrochloride

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
1G	20.00		In Stock	Estimated to ship on 20 September 2026
5G	85.00		In Stock	Estimated to ship on 20 September 2026
25G	365.00		In Stock	Estimated to ship on 20 September 2026

Applications : This is an advanced key intermediate in the preparation of Ivabradine and related analogs, which is an orally bioavailable, hyperpolarization-activated, cyclic nucleotide-gated (HCN) channel blocker, used for the symptomatic management of stable heart-related chest pain and heart failure not fully managed by beta blockers.

References : Thollon C. et al.: Br. J. Pharmacol.,112(1), 37-42, 1994; Fang Y. et al.: J. Cardiovasc Pharmacol., 59(3), 260-7, 2012; Kroller-Schon S. et al.: Basic Res Cardiol.,106(6), 1147-58, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.