2-(1-Isopropyl-1H-1,2,4-triazol-5-yl)-9-methoxy-5,6-dihydroimidazo[1,2-d]pyrido[3,4-f][1,4]oxazepine

SI-2301

2-(1-Isopropyl-1H-1,2,4-triazol-5-yl)-9-methoxy-5,6-dihydroimidazo[1,2-d]pyrido[3,4-f][1,4]oxazepine, 97%

CAS No. : [1282513-56-7]

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Applications : This is an advanced key intermediate in the preparation of GDC-0326 related analogs, which is a potent and selective PI3Kα inhibitor.

References : Heffron P. T. et al.: J. Med. Chem., 59(3), 985-1002,2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.