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2-(2,5-Dioxopyrrolidin-1-yl)ethyl ethyl fumarate

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2-(2,5-Dioxopyrrolidin-1-yl)ethyl ethyl fumarate, >98%

Price And Availability
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25MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
50MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
100MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
250MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
500MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C12H15NO6
Mol. Weight :
269.25
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Diroximel fumarate, which is an orally active, well-tolerated monomethyl fumarate (MMF) proagent in controlled-release form. Diroximel fumarate is considered pharmacologically equivalent to its active metabolite, Dimethyl fumarate (DMF). With a favourable safety and efficacy profile, Diroximel fumarate shows potential for multiple sclerosis (MS) research. As a Nrf2 activator, it alleviates MGO-induced pain hypersensitivity.

References : Angela W. et al.: Neurology (P1.403), Apr 2018; Yousuf M. S. bioRxiv 12, 22, 572877, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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