2,3:4,5-Di-O-isopropylidene-beta-D-fructopyranose-d12

SL-6224

2,3:4,5-Di-O-isopropylidene-beta-D-fructopyranose-d₁₂, >98%

Isotopic Purity : 99 atom % D

Synonyms : 2,3:4,5-Bis-O-isopropylidene-β-D-fructopyranose-d₁₂; Topiramate-d₁₂ related compound A

IUPAC Name : ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetrakis(methyl-d₃)tetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-3a-yl)methanol

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : This is a deuterium labelled version an advanced key intermediate in the preparation of Topiramate and related analogs. Topiramate is a mutil-targeted inhibitor, including voltage-gated sodium channel and calcium channel, AMPA/kainate receptor and carbonic anhydrase, used to treat epilepsy.

References : Taverna S. et al.: J. Pharmacol Exp Ther., 288(3), 960-968, 1999; Gryder D. S. et al.: J. Neurosci., 23(18), 7069-7074, 2003; Yang Y. et al.: Brain Res., 804(2), 169-176, 1998; Kaminski R. M. et al.: Neuropharmacology 46(8), 1097-1104, 2004; Koh S. et al.: Ann Neurol., 50(3), 366-372, 2001; Nakamura J. et al. Eur J. Pharmacol., 254(1-2), 83-89, 1994.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.