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CAS No. : [40055-37-6]
Synonyms : 3-(4,5-Dihydrooxazol-2-yl)pyridine; 3-(2-Oxazolin-2-yl)pyridine; Nicorandil EP impurity D
IUPAC Name : 2-(pyridin-3-yl)-4,5-dihydrooxazole
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 1G | 395.00 | In Stock | Estimated to ship on 20 September 2026 | |
| 5G | 1095.00 | In Stock | Estimated to ship on 20 September 2026 | |
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| Chemical Properites | |
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Mol. Formula : C8H8N2O | Mol. Weight : 148.16 |
Appearance : Pale brown solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : 2-(3-Pyridyl)-2-oxazoline is an impurity of Nicorandil (Nicorandil EP impurity D), which is a potassium channel activator, and stimulates guanylate cyclase to increase formation of cyclic GMP (cGMP), used to treat angina.
References : Sato T. et al. J. Am. Coll. Cardiol., 35(2), 514-518, 2000; Akao M.et al.: J. Am. Coll. Cardiol., 40(4), 803-810, 2002; Szczepanik A. M. et al.: J. Pharmacol Exp Ther., 278(2), 913-920, 1996; Teshima Y. et al.: Brain Res., 990(1-2), 45-50, 2003; Sathish V. et al.: Mol Cell Biochem., 243(1-2), 133-138, 2003.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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