(2-((3R,4S)-3-Hydroxytetrahydro-2H-pyran-4-yl)-6-methyl-1-oxo-1,2,3,4-tetrahydroisoquinolin-7-yl)boronic acid pinacol ester

SI-1622

(2-((3R,4S)-3-Hydroxytetrahydro-2H-pyran-4-yl)-6-methyl-1-oxo-1,2,3,4-tetrahydroisoquinolin-7-yl)boronic acid pinacol ester, 97%

CAS No. : [2115022-72-3]

IUPAC Name : 2-((3R,4S)-3-Hydroxytetrahydro-2H-pyran-4-yl)-6-methyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinolin-1(2H)-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : This is an advanced key intermediate in the preparation of PF-06827443 related analogs, which is a potent, orally bioavailable, and CNS-penetrant M1-selective positive allosteric modulator (PAM).

References : Davoren E. J. et al.: J. Med. Chem., 60(15), 6649-6663, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.