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2-(5-Amino-2-propoxyphenyl)-5,6-diethylpyrimidin-4(3H)-one

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SI-4599

2-(5-Amino-2-propoxyphenyl)-5,6-diethylpyrimidin-4(3H)-one, 97%

CAS No. : [1229017-39-3]

IUPAC Name : 2-(5-Amino-2-n-propoxyphenyl)-5,6-diethyl-4(3H)-pyrimidone

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100MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C17H23N3O2
Mol. Weight :
301.38
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an advanced key intermediate in the preparation of TPN-171 and related analogs, which is a TPN-171 is a potent PDE5 inhibitor for the treatment of pulmonary arterial hypertension.

References : Wang Z. et al.: J. Med. Chem., 62(10), 4979-4990, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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