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2-Amino-2′-deoxy-2′,2′-dimethyl-adenosine

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2-Amino-2′-deoxy-2′,2′-dimethyl-adenosine, >98%

CAS No. : [2080436-77-5]

Synonyms : Adenosine impurity 27

IUPAC Name : (2R,3S,5R)-5-(2,6-Diamino-9H-purin-9-yl)-2-(hydroxymethyl)-4,4-dimethyltetrahydrofuran-3-ol

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Chemical Properites
Mol. Formula :
C12H18N6O3
Mol. Weight :
294.32
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Adenosine, which is a naturally occurring molecule that signals through four G protein-coupled receptors (A1, A2A, A2B, A3). It influences cellular processes such as neuronal activity, vascular function, platelet aggregation, and blood cell regulation.

References : Fredholm B. B. et al.: Cell Death Differ., 14(7), 1315-1323, 2007; Borea P. A. et al.: The State of the Art. Physiol Rev., 98(3), 1591-1625, 2018; Eltzschig H. K. Anesthesiology 111(4), 904-915, 2009; Zhou X. T. et al.: Oncol Rep., 41(2), 829-838, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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