2-Amino-4-(2-pyridyl)pyrimidine

SL-3617

2-Amino-4-(2-pyridyl)pyrimidine, >98%

CAS No. : [66521-65-1]

MDL No. : MFCD00138711

IUPAC Name : 4-(Pyridin-2-yl)pyrimidin-2-amine

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
1G	355.00		Back Order	Estimated to ship on 20 September 2026
5G	955.00		Back Order	Estimated to ship on 20 September 2026

Applications : 2-Amino-4-(2-pyridyl)pyrimidine is an advanced key intermediate in the preparation of Nilotinib related analogs. Nilotinib is a selective Bcr-Abl tyrosine kinase inhibitor, for the potential treatment of various leukemias, including chronic myeloid leukemia (CML).

References : Weisberg E. et al. Blood, 109(5), 2112-2120, 2007; Liu Y. et al.: J. Hepatol, 55(3), 612-625, 2011; Hochhaus A. et al.: Cell Cycle, 10(2), 250-260, 2011; Ammoun S. et al.: Neuro Oncol., 13(7), 759-766, 2011; Rhee C. K. et al.: Respiration., 82(3), 273-287, 2011; Weisberg E. et al. Cancer Cell, 7(2), 129-141, 2005.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.