2-Amino-4-(3-pyridyl)pyrimidine

SL-3616

2-Amino-4-(3-pyridyl)pyrimidine, >98%

CAS No. : [66521-66-2]

MDL No. : MFCD01317832

IUPAC Name : 4-(Pyridin-3-yl)pyrimidin-2-amine

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
1G	15.00		In Stock	Estimated to ship on 20 September 2026
5G	55.00		In Stock	Estimated to ship on 20 September 2026
10G	75.00		In Stock	Estimated to ship on 20 September 2026
25G	155.00		In Stock	Estimated to ship on 20 September 2026
100G	465.00		In Stock	Estimated to ship on 20 September 2026

Applications : 2-Amino-4-(3-pyridyl)pyrimidine is an advanced key intermediate in the preparation of Nilotinib and related analogs. Nilotinib is a selective Bcr-Abl tyrosine kinase inhibitor, for the potential treatment of various leukemias, including chronic myeloid leukemia (CML).

References : Weisberg E. et al. Blood, 109(5), 2112-2120, 2007; Liu Y. et al.: J. Hepatol, 55(3), 612-625, 2011; Hochhaus A. et al.: Cell Cycle, 10(2), 250-260, 2011; Ammoun S. et al.: Neuro Oncol., 13(7), 759-766, 2011; Rhee C. K. et al.: Respiration., 82(3), 273-287, 2011; Weisberg E. et al. Cancer Cell, 7(2), 129-141, 2005.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.