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2′-Carboxy azilsartan methyl ester

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2′-Carboxy azilsartan methyl ester, >98%

CAS No. : [1675221-59-6]

IUPAC Name : 4'-((2-Ethoxy-7-(methoxycarbonyl)-1H-benzo[d]imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-carboxylic acid

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Chemical Properites
Mol. Formula :
C25H22N2O5
Mol. Weight :
430.46
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an advanced key intermediate in the synthesis of Azilsartan, which is a specific and potent angiotensin II type 1 receptor antagonist. Azilsartan is used to treat high blood pressure (hypertension).

References : Ding H. X. et al.: Bioorg. Med. Chem. 21(11), 2795-2825, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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