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(2-Chloro-5-iodophenyl)(4-ethoxyphenyl)methanol

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SL-3707

(2-Chloro-5-iodophenyl)(4-ethoxyphenyl)methanol, >98%

CAS No. : [1298086-29-9]

Synonyms : Dapagliflozin impurity 2

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Chemical Properites
Mol. Formula :
C15H14ClIO2
Mol. Weight :
388.63
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Dapagliflozin (Dapagliflozin impurity 2), which is a sodium-glucose co-transporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes.

References : Pedersen M. G. et al.: Sci Rep. 6, 31214, 2016; Yoon-Kyung Chang, et al.: PLoS One 11(7), e0158810, 2016; Chiba Y. et al.: PLoS One 11(3) e0150756,2016; Akahane K. et al.: Drug Res (Stuttg) 65(8), 416-421, 2015; Sakaeda T. et al.: Int. J. Med Sci., 15(9), 937-943, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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