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2’-Deschloro-2’-hydroxy dasatinib

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SL-3020

2’-Deschloro-2’-hydroxy dasatinib, >98%

CAS No. : [1159977-25-9]

Synonyms : Dasatinib impurity 13

IUPAC Name : N-(2-Hydroxy-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide

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Chemical Properites
Mol. Formula :
C22H27N7O3S
Mol. Weight :
469.56
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : 2’-Deschloro-2’-hydroxy dasatinib is an impurity of Dasatinib, which is a dual Bcr-Abl and Src family tyrosine kinase inhibitor, used in the treatment of cancers and immune diseases.

References : Kovackova S. et al.: J. Med. Chem., 58(8), 3393-3410, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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