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2-Deschloro vismodegib

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2-Deschloro vismodegib, >98%

CAS No. : [1195072-86-6]

Synonyms : Vismodegib mono deschloro impurity 2

IUPAC Name : N-(4-Chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide

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Chemical Properites
Mol. Formula :
C19H15ClN2O3S
Mol. Weight :
386.85
Appearance :
Pale brown solid
Melting Point :
Not available
Solubility :
Acetonitrile : H2O (1:1)
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Vismodegib, which is a potent, novel and specific hedgehog inhibitor. Vismodegib is used to treat basal cell carcinoma (BCC), a type of skin cancer.

References : Scales S. J. et al.: Trends Pharmacol Sci., 30(6), 303-312, 2009; Zhang Y. et al.: Neoplasia 11(1), 96-101, 2009; Tian F. et al.: Anticancer Res., 32(1), 89-94, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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