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2-Desmethylbenzaldehyde tolvaptan

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2-Desmethylbenzaldehyde tolvaptan, >98%

CAS No. : [1432725-24-0]

IUPAC Name : (4-Amino-2-methylphenyl)(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)methanone

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Chemical Properites
Mol. Formula :
C18H19ClN2O2
Mol. Weight :
330.81
Appearance :
Beige solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an advanced key intermediate in the synthesis of Tolvaptan and related analogs. Tolvaptan is a selective, competitive arginine vasopressin receptor 2 antagonist. It can be used for the research of hyponatremia.

References : Wu Y. et al.: Biochem Pharmacol., 95(4), 324-36, 2015; El-Shabrawy M. et al.: Pharmacol Res Perspect., 8(5), e00659, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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