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2-(Dimethylamino-d6)-2-oxoethyl 2-(4-hydroxyphenyl)acetate

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SL-6067

2-(Dimethylamino-d6)-2-oxoethyl 2-(4-hydroxyphenyl)acetate, >98% (CP)

Isotopic Purity : 99 atom % D

CAS No. : [1346603-09-5]

Related CAS No. : [59721-16-3] of the unlabelled compound

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Chemical Properites
Mol. Formula :
C12H9D6NO4
Mol. Weight :
243.29
Appearance :
Pale brown solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an advanced deuterium labelled version key intermediate in the preparation of Camostat and related analogs. Camostat is a trypsin-like protease inhibitor, used for the treatment of chronic pancreatitis and postoperative reflux esophagitis.

References : Coote K. et al.: J. Pharmacol Exp Ther., 329(2), 764-774, 2009; Okuno M. et al.: Gastroenterology 120(7), 1784-1800, 2001; Yamamoto A. et al.: Pharm Res., 11(10), 1496-1500, 1994; Gibo J. et al.: Lab Invest., 85(1), 75-89, 2005; Su S. B. et al.: Pancreas 23(2), 134-140, 2001.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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