2-Methylsulfanylmethyl propanoic acid

SL-10034

2-Methylsulfanylmethyl propanoic acid, >98%

CAS No. : [1248666-78-5]

IUPAC Name : 2-Methyl-3-(methylsulfinyl)propanoic acid

Price And Availability
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25MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
50MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
100MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
250MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
500MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026

Applications : This is an impurity of Thiorphan, which is a selective neprilysin (NEP) inhibitor that competitively blocks NEP activity, preventing neuropeptide degradation such as substance P (SP) and neurokinin A (NKA). In neonatal brain injury research, Thiorphan raises SP and NKA levels, activates NK1/NK2 receptors and related pathways, inhibits overactive NMDA receptors, and protects neocortical neurons from excitotoxicity. It may also reduce NEP-driven bronchoconstriction, making it relevant for respiratory disease studies.

References : Whyteside A. R. et al.: FEBS Lett., 582(16), 2382-6, 2008; Cheung D. et al.: Am Rev Respir Dis., 145(6), 1275-80, 1992; Medja F. et al.: Brain 129(Pt 12), 3209-23, 2006.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.