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(2R)-1-(9H-Purin-6-ylamino)-2-propanol

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SL-1896

(2R)-1-(9H-Purin-6-ylamino)-2-propanol, >98%

CAS No. : [1244022-52-3]

MDL No. : MFCD20682839

Synonyms : Tenofovir related compound 14

IUPAC Name : (2R)-1-[(7H-purin-6-yl)amino]propan-2-ol

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Chemical Properites
Mol. Formula :
C8H11N5O
Mol. Weight :
193.21
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a reagent for the synthesis of Tenofovir disoproxil fumarate, which is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.

References : Murphy R. A. et al.: Int. J. Mol. Sci.18(3), 2017; Musumeci G. et al.: Sci. Rep. 7, 41018, 2017; Wahl A. et al.: Sci. Rep.7, 41098, 2017; Menne S. et al.: J. Antimicrob Agents Chemother., 49(7), 2720-2728, 2005.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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