3-(3,5-Difluorophenoxy)propanoic acid

SL-9968

3-(3,5-Difluorophenoxy)propanoic acid, >98%

CAS No. : [844648-19-7]

Synonyms : Tegoprazan impurity 12

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
50MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
100MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
250MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
500MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026

Applications : This is an impurity of Tegoprazan, which is a potassium-competitive acid blocker that acts as a reversible, orally active, and selective inhibitor of gastric H+/K+-ATPase. It reduces gastric acid secretion and motility in porcine, canine, and human H+/K+-ATPase in vitro, with IC50 values between 0.29-0.52 μM. Studies indicate that Tegoprazan improves colitis and enhances intestinal epithelial barrier function in mice. Tegoprazan is used in research related to inflammatory bowel disease, gastric acid-related conditions, and motility impairments.

References : Son M. et al.: Front Immunol.,13, 870817, 2022; Kim D. K, et al.: J. Pharmacol Exp Ther., 369(3), 318-327, 2019; Takahashi N. et al.: J. Pharmacol Exp Ther., 364(2), 275-286, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.