3-(3-Cyclopropylphenyl)-3-((5-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy)pyridin-2-yl)amino)propanoic acid

SI-5499

3-(3-Cyclopropylphenyl)-3-((5-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy)pyridin-2-yl)amino)propanoic acid, >98% (HPLC)

CAS No. : [2378617-67-3]

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
Note: SI-5499 is not in stock but can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or Request A Quote. We respond promptly. Thank You!

Applications : This is an orally bioavailable pan αv integrin inhibitor.This can increases the αvβ6, αvβ3, αvβ5 and αvβ8 binding affinities with pIC50 values of 7.8, 8.4, 8.4 and 7.4, respectively. This can be used for the potential treatment of idiopathic pulmonary fibrosis.

References : Anderson N. A. et al.: J. Med Chem., 62(19), 8796-8808, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.