(3-(4-(tert-Butyl)benzamido)-2-(((tert-butyldimethylsilyl)oxy)methyl)phenyl)boronic acid pinacol ester

SI-2005

(3-(4-(tert-Butyl)benzamido)-2-(((tert-butyldimethylsilyl)oxy)methyl)phenyl)boronic acid pinacol ester, 97%

CAS No. : [1454614-81-3]

IUPAC Name : 4-(tert-Butyl)-N-(2-(((tert-butyldimethylsilyl)oxy)methyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)benzamide

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Applications : This is an advanced key intermediate in the preparation of SI-1996 related analogs, which is a potent, highly selective BTK inhibitor.

References : Kawahata W. et al.: J. Med. Chem., 61(19), 8917-8933, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.