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3-Chloro azelastine hydrochloride (isomer)

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3-Chloro azelastine hydrochloride (isomer), >98%

Related CAS No. : [37933-01-0] of the free base compound

IUPAC Name : 4-(3-Chlorobenzyl)-2-(1-methylazepan-4-yl)phthalazin-1(2H)-one

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Chemical Properites
Mol. Formula :
C22H24ClN3O . HCl
Mol. Weight :
418.36
Appearance :
Pale brown solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an isomer of Azelastine, an antihistamine medication. Azelastine is a potent and selective histamine H1 antagonist, which may be used for research into allergic rhinitis, asthma, diabetic hyperlipidaemia, and SARS-CoV-2.

References : Craig L. F.: Expert Rev Clin Immunol., 1(2), 191-201, 2005; Mohamed M. E. et al.: Arch Physiol Biochem., 1-8, 2020; Carlos D. Z. et al.: Pharmacol Res Perspect., 7(6), e00531, 2019; Li Y. et al.: Acta Pharmacol Sin., 1-7, 2020; Shao-Cheng L. et al.: Eur Arch Otorhinolaryngol., 274(2), 845-853, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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