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3-Demethyl colchicine 3-O-β-D-glucuronide

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SL-6535

3-Demethyl colchicine 3-O-β-D-glucuronide, >98%

CAS No. : [913079-71-7]

Synonyms : (7S)-7-(Acetylamino)-5,6,7,9-tetrahydro-1,2,10-trimethoxy-9-oxobenzo[a]heptalen-3-yl β-D-glucopyranosiduronic acid

IUPAC Name : (2S,3S,4S,5R,6S)-6-(((S)-7-Acetamido-1,2,10-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-3-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid

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Chemical Properites
Mol. Formula :
C27H31NO12
Mol. Weight :
561.54
Appearance :
Pale yellow solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a metabolite of Colchicine, which is a microtubule polymerization inhibitor, used to treat gout and behcet's disease.

References : Bonfoco E. et al.: Exp Cell Res., 218(1), 189-200,1995; Hastie S. B. Pharmacol Ther., 51(3), 377-401,1991; Otani K. et al.: Sci Rep., 6, 32587, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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