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3-Desmorpholinyl-3-hydroxyethylamino gefitinib

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SL-3338

3-Desmorpholinyl-3-hydroxyethylamino gefitinib, >98%

CAS No. : [847949-56-8]

IUPAC Name : 2-((3-((4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)amino)ethanol

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Chemical Properites
Mol. Formula :
C20H22ClFN4O3
Mol. Weight :
420.87
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a metabolite of Gefitinib, which is an orally active epidermal growth factor receptor tyrosine kinase inhibitor that blocks signal pathways implicated in solid tumour growth and metastasis.

References : Ranson M. et. al.: J. Clin. Pharm. Ther., 29(2), 95, 2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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