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3-Hydroxy midostaurin

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3-Hydroxy midostaurin, >98% (HPLC)

CAS No. : [179237-49-1]

Synonyms : CGP 52421

IUPAC Name : N-((5R,7R,8R,9S)-14-Hydroxy-8-methoxy-9-methyl-16-oxo-6,7,8,9,15,16-hexahydro-5H,14H-17-oxa-4b,9a,15-triaza-5,9-methanodibenzo[b,h]cyclonona[jkl]cyclopenta[e]-as-indacen-7-yl)-N-methylbenzamide

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MG495.00
In Stock  Estimated to ship on 20 September 2026
10MG895.00
In Stock  Estimated to ship on 20 September 2026
25MG1695.00
In Stock  Estimated to ship on 20 September 2026
50MG2995.00
In Stock  Estimated to ship on 20 September 2026
100MG5995.00
In Stock  Estimated to ship on 20 September 2026
We accept
Chemical Properites
Mol. Formula :
C35H30N4O5
Mol. Weight :
586.65
Appearance :
Pale yellow solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : 3-Hydroxy midostaurin is a metabolite of Midostaurin, which is a multi-targeted kinase inhibitor, used for the treatment of acute myeloid leukemia (AML), myelodysplastic syndrome (MDS) and advanced systemic mastocytosis.

References : Fabbro D. et al.: Pharmacol Ther., 82(2-3), 293-301, 1999; Ikegami Y. et al.: Jpn. J. Pharmacol., 70(1), 65-72, 1996; Manley P. W. et al.: Biochemistry 57(38), 5576-5590, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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